Basic Information
VIS ID
TVIS30014899
Fusion event
HIV-LOC107984492 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
13010873/12857939 (Hg38)
End
13010678/12857939 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107984492
Nearest miRNA
hsa-mir-1244-3/Upstream/93196; hsa-let-7i/Downstream/57890;
Nearest TSS
ENST00000382841/Upstream/33554; ENST00000534831/Downstream/32843;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/44524, chr12-CpG: 49/Downstream/33169
Nearby gene
RPL13AP20(No orient, 17537)
Upstream sequence
ggaagtcaaggctgcagtgagccatgatcgcaccactgcattccaccctgtctcaaaaaagaaaaaaaaaGGAGTATATTCAAAATATTTGTTTGAATAT
Downstream sequence
TCATGAAATATCTCTCAAGAATTACACAAGAACTATGTAACAGGTAACATTGATACCTCCAGGAAGGGAAACCAGGTGTTCAGTGGGCTAAGGAAGGGAA
Target sequence
aaagaaacaaacaaacaaaaattagccaggcatggtggcatgagcctgtggttgcagctactccagaggctgaaggggaggatcactggagcctgggaagtcaaggctgcagtgagccatgatcgcaccactgcattccaccctgtctcaaaaaagaaaaaaaaaGGAGTATATTCAAAATATTTGTTTGAATAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate