Basic Information
VIS ID
TVIS30014908
Fusion event
HIV-chr12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
22552354/22399420 (Hg38)
End
22552661/22399420 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/4726026; hsa-let-7i/Downstream/1813001;
Nearest TSS
ENST00000382841/Upstream/1345; ENST00000508615/Downstream/37621;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/63688, chr12-CpG: 71/Downstream/144426
Upstream sequence
ctttcatagtcacttaccaggaatacaccaataacctaagaaagctttgttcttttaacaaaaataagaccaaaatctaattttgtctcaacatactttt
Downstream sequence
ttatttctagtgtccttaattacatatattaattaattcttagctcttagtaaacttaattttcagcaaaaatgaggaagtatgccatttcataactatg
Target sequence
gatactaagcctcatttttaaaccattataataaattcatttcatttcagccagcctaactacataagattatctctcttcatattatctctttctctttctctctctccccccaccccaatttctatgtccatttagtttttgtccttcatttccctctttttcatttgaaacaagctttaaactctaaaatagaacaataattttctttttctcagcaaaaaacacatccttatactttataacttatcttac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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