VISDB Viral Integration Site DataBase

VIS ID

TVIS30014909

Fusion event

HIV-KRAS integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr12

Cytoband

p12.1

Reference genome

Start

End

25393061/25240184 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-18a-3p ; hsa-mir-143-3p ; hsa-let-7g-5p ; hsa-let-7a-5p ; hsa-mir-181c-5p ; hsa-mir-155-5p ; hsa-mir-96-5p ; hsa-mir-216b-5p ; hsa-mir-622 ; hsa-mir-126-3p ; hsa-mir-217 ; hsa-mir-193b-3p ; hsa-mir-181a-5p ; hsa-mir-16-5p ; hsa-mir-134-5p ; hsa-mir-224-5p ; hsa-mir-452-5p ; hsa-mir-152-3p ; hsa-mir-340-5p ; hsa-mir-433-3p ; hsa-mir-487b-3p ; hsa-mir-365a-3p ; hsa-mir-200c-3p ; hsa-mir-27a-3p ; hsa-mir-206 ; hsa-mir-4314 ; hsa-mir-6716-5p ; hsa-mir-6866-5p ; hsa-mir-3148 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-892b ; hsa-mir-514a-5p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-429 ; hsa-mir-200b-3p ; hsa-mir-193a-3p ; hsa-mir-183-5p ; hsa-mir-877-5p ; hsa-mir-5010-3p ; hsa-mir-642a-5p ; hsa-mir-642b-5p ; hsa-mir-124-5p ; hsa-mir-671-5p ; hsa-mir-873-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-4666b ; hsa-let-7c-3p ; hsa-mir-4328 ; hsa-mir-4698 ; hsa-mir-1-3p ; hsa-mir-199a-5p ; hsa-mir-543 ; hsa-mir-384 ; hsa-mir-4689 ; hsa-mir-613

Nearest miRNA

hsa-mir-1244-3/Upstream/1027689; hsa-let-7i/Downstream/633836;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/44719, chr12-CpG: 123/Downstream/10148

Nearest cancer related gene

KRAS(OG, No orient, 0)

Upstream sequence

aaaaatagtacagcgaatAgcctcagcctcccaaagtgctaagattacaggcatgagccaccatatctggcttatttctactaatttctataTTAAGATC

Downstream sequence

CCAATAATTTAACTGTTCCATAACCTACACATTATGAAATAATAATGGTTAAGAGACGCCAGAAATGTAATGCTCTTAAGTATAAAGCCTCTAAATTAAG

Target sequence

attacaggcatgagccaccatatctggcttatttctactaatttctataTTAAGATC