Basic Information
VIS ID
TVIS30014910
Fusion event
HIV-CCDC91 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
28436644/28283711 (Hg38)
End
28436792/28283711 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC91
miRNAs that regulate target gene
hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5689
Nearest miRNA
hsa-mir-1244-3/Upstream/2409632; hsa-let-7i/Downstream/14039989;
Nearest TSS
ENST00000382841/Upstream/15108; ENST00000539904/Downstream/18923;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/92737, chr12-CpG: 91/Downstream/865331
Upstream sequence
gttttgcagatgataagagtttttcggattttggaatatttgcatatatatagtatttcttggggatgagacccaagtgtaaacatgaaatttgtgtttt
Downstream sequence
tgtcaaattttggattattttagatttcagggttttggattagggatgcacaatctgTGTTAGTAATGAATTTAGTGGGGGTATGTTTGTCTCTGCCAGG
Target sequence
atgtatagcttatacatatagcctgaatgtaattttatacaatattttaaagattttttaaatatgaaatgaaattttgactgtgacctgtcacatgggatcaagtgcagaattttccatttatgatatcatgtggatgctcaaaaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate