Basic Information
VIS ID
TVIS30014912
Fusion event
HIV-FGD4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
32670812/32517878 (Hg38)
End
32671000/32517878 (Hg38)
Orient
+
Location type
Intronic
Target gene
FGD4
miRNAs that regulate target gene
hsa-mir-4487 ; hsa-mir-526b-5p ; hsa-mir-431-5p ; hsa-mir-6716-5p ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-613 ; hsa-mir-129-5p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-3942-3p ; hsa-mir-6836-3p ; hsa-mir-5100 ; hsa-mir-4797-3p ; hsa-mir-545-5p ; hsa-mir-10b-3p ; hsa-mir-4266 ; hsa-mir-499a-5p ; hsa-mir-208b-3p ; hsa-mir-208a-3p ; hsa-mir-302f ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-197-3p ; hsa-mir-4742-3p ; hsa-mir-339-5p ; hsa-mir-490-5p ; hsa-mir-7153-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/6643799; hsa-let-7i/Downstream/9805822;
Nearest TSS
ENST00000382841/Upstream/15661; ENST00000525053/Downstream/16446;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/117774, chr12-CpG: 72/Downstream/161318
Upstream sequence
gggaggctaaggtgggaggattgcttgagcctgaaaggttgaggctgcagtgagccgagaccatgctgctgcactccatcctgggtgacagagtgagacc
Downstream sequence
ACTAAGTTTTAGGACTAACTTCAGGATTGACGTGTGTAGACAACATGTACAAGATTCTTGTGAAAGACTATCTGTCTAGGAACATGACTACTGCCTACAT
Target sequence
ctgtctcaaaaaaaaaaaGTTTTGGAAGAATTCAACTTGAAATCATTTTGGAGATTCCCTCCCACCCAACCCCCAATATCGTTAGTATTTTTTTGCATGTAACATTTACTGTTTATTCTGCCTACTTTCTGCCATCATCATAGTTTTAACATTGGTGCTATAGCATATTTATGTCAGCTTTATGACTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate