Basic Information
VIS ID
TVIS30014913
Fusion event
HIV-KIF21A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
End
39760831/39367334 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/13493255; hsa-let-7i/Downstream/2956366;
Upstream sequence
GTAATGGCTAAAACCCACCATGTTAAGGGATATAAAAGATGTGGAATTTCACATTATTAGTTCAGTTACAGGCACTTTTTGAGATGGACTTCTCAGTATA
Downstream sequence
ATAGTGTATTATTTTTTAAATAGAAGAAAACACTGAGATTCCATTGTTGGCCATTTGCTGACATTTGCAGCTTCCATTCCAAAACTGTTATAGTAGAACA
Target sequence
AGCATCTATTTGGGGACACACTCTGGTTTGACACACATGAATGGTAAAAATGGCATGTGAACGAGAGCTCTGAACATTCATCTGGGTACTGGCAGTTGTCCGGGATAAAGCACCCAACTTCAAACACTGCATCATCTGAAAAAGGGGAAGAAACAAGGACTTTACTTGAACAATAAACAAGATACTATACAATCCAAAGTCTGAGGTAATGGCTAAAACCCACCATGTTAAGGGATATAAAAGATGTGGAATTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate