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TVIS30014914
Basic Information
VIS ID
TVIS30014914
Fusion event
HIV-ABCD2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
39997835/39604033 (Hg38)
End
39997451/39604033 (Hg38)
Orient
-
Location type
Intronic
Target gene
ABCD2
miRNAs that regulate target gene
hsa-mir-411-5p
;
hsa-mir-3117-3p
;
hsa-mir-3607-3p
;
hsa-mir-1208
;
hsa-mir-8083
;
hsa-mir-3169
;
hsa-mir-4759
;
hsa-mir-4276
;
hsa-mir-1257
;
hsa-mir-15b-3p
;
hsa-mir-5187-3p
;
hsa-mir-5190
;
hsa-mir-4699-3p
;
hsa-mir-5094
;
hsa-mir-4724-5p
;
hsa-mir-4671-3p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301a-3p
;
hsa-mir-301b-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-4267
;
hsa-mir-5586-5p
;
hsa-mir-605-5p
;
hsa-mir-576-5p
;
hsa-mir-4263
;
hsa-mir-3074-5p
;
hsa-mir-627-3p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-5003-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/13729954; hsa-let-7i/Downstream/2719667;
Nearest TSS
ENST00000382841/Upstream/160643;
ENST00000405531/Downstream/15718;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/160336
,
chr12-CpG: 108/Downstream/501127
Upstream sequence
ACCACTTCTCCTGCTGGTGTAATTATGGGAACATTTTCACAAATAATTCCGTGATCCACATCAATAACTTTTCCTGTAATTAAGAAAAAGTGTAAGATAC
Downstream sequence
AAACATTATCACAGGTTTCTGATTAAATAACGTAAATTATTATGCAGTATAACAGGTAATTTCAATTATAAAGATAATTCACAGTAATAAATCACAGAAA
Target sequence
AATTTCCTATTGTTCCCCAAAATTACCTTGTACACTATAATTTTGATTTTCAACCTGGCAATAAAGCAGTAGAAATCAAATTTCTCTTTTCTCTCTGCTTTCTGAGGAATAACTGCTTCTGTAATTGAGCCACTGTGCATACCTTTCTTGATTTCCCCTTTCCAAATGCTCCTCCAAGTATTTAACATAAGGTACATGAATTCTGAGTTGTTTTGTATTAGTGTGATGGCAACAATCAGAAGATTCTTGAATATC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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