Basic Information
VIS ID
TVIS30014914
Fusion event
HIV-ABCD2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
End
39997451/39604033 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/13729954; hsa-let-7i/Downstream/2719667;
Upstream sequence
ACCACTTCTCCTGCTGGTGTAATTATGGGAACATTTTCACAAATAATTCCGTGATCCACATCAATAACTTTTCCTGTAATTAAGAAAAAGTGTAAGATAC
Downstream sequence
AAACATTATCACAGGTTTCTGATTAAATAACGTAAATTATTATGCAGTATAACAGGTAATTTCAATTATAAAGATAATTCACAGTAATAAATCACAGAAA
Target sequence
AATTTCCTATTGTTCCCCAAAATTACCTTGTACACTATAATTTTGATTTTCAACCTGGCAATAAAGCAGTAGAAATCAAATTTCTCTTTTCTCTCTGCTTTCTGAGGAATAACTGCTTCTGTAATTGAGCCACTGTGCATACCTTTCTTGATTTCCCCTTTCCAAATGCTCCTCCAAGTATTTAACATAAGGTACATGAATTCTGAGTTGTTTTGTATTAGTGTGATGGCAACAATCAGAAGATTCTTGAATATC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate