Basic Information
VIS ID
TVIS30014917
Fusion event
HIV-ARID2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
46151066/45757283 (Hg38)
End
46151262/45757283 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARID2
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-155-5p ; hsa-mir-424-3p ; hsa-mir-15b-5p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-374a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4474-3p ; hsa-mir-222-5p ; hsa-mir-4501 ; hsa-mir-545-5p ; hsa-mir-802 ; hsa-mir-203a-3p ; hsa-mir-194-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-127-5p ; hsa-mir-6071 ; hsa-mir-7160-5p ; hsa-mir-8077 ; hsa-mir-4663 ; hsa-mir-873-3p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-3692-5p ; hsa-mir-93-3p ; hsa-mir-4329 ; hsa-mir-6728-3p ; hsa-mir-4499 ; hsa-mir-5584-3p ; hsa-mir-4277
Nearest miRNA
hsa-mir-1244-3/Upstream/3433424; hsa-let-7i/Downstream/1430529;
Nearest TSS
ENST00000382841/Upstream/27367; ENST00000480128/Downstream/79478;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/26611, chr12-CpG: 115/Downstream/232495
Nearest cancer related gene
ARID2(TSG, No orient, 0)
Upstream sequence
GCCAGCATTCCCAAACtgttaagtaggtggactgtggaaaatgtgttctgtacttaaatactatttggaaaaacagttaaacatcgttcttttctgcaac
Downstream sequence
CAACTGGGATAGTCTTGAAAAATGTTTAACTTACTGAGACAGATGTGAAAGCCCATTGCCCTTCTAGTTCTGGGATGATTGATCATGATCACAGAGAGCT
Target sequence
acttctcaaactaatatgcttataatgtatcttctgactgtccacagaatttcccaaacacatttgagcacATATTGTCCCATCTCTTCCCACTCCTGACCTCACCAGCCCCTAGCATACGTATCACTCACAGGGTAAATGTGAAGTTTTAGGAAATGTTGCCGTCAGTACACAAACTTGCTAGATAAAATGGACC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate