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TVIS30014922
Basic Information
VIS ID
TVIS30014922
Fusion event
HIV-SLC38A1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
46659299/46265516 (Hg38)
End
46659333/46265516 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC38A1
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-let-7b-5p
;
hsa-mir-30a-5p
;
hsa-mir-218-5p
;
hsa-mir-320d
;
hsa-mir-877-3p
;
hsa-mir-484
;
hsa-mir-570-3p
;
hsa-mir-6074
;
hsa-mir-4726-3p
;
hsa-mir-3671
;
hsa-mir-607
;
hsa-mir-340-5p
;
hsa-mir-374a-5p
;
hsa-mir-5590-3p
;
hsa-mir-142-5p
;
hsa-mir-570-5p
;
hsa-mir-548ba
;
hsa-mir-548ai
;
hsa-mir-548ag
;
hsa-mir-548m
;
hsa-mir-4652-3p
;
hsa-mir-4743-3p
;
hsa-mir-4639-5p
;
hsa-mir-6888-3p
;
hsa-mir-374b-5p
;
hsa-mir-3148
;
hsa-mir-6124
;
hsa-mir-215-3p
;
hsa-mir-6773-3p
;
hsa-mir-4317
;
hsa-mir-8076
;
hsa-mir-3688-3p
;
hsa-mir-5692b
;
hsa-mir-5692c
;
hsa-mir-369-3p
;
hsa-mir-4517
;
hsa-mir-5583-3p
;
hsa-mir-1277-5p
;
hsa-mir-2113
;
hsa-mir-889-3p
;
hsa-mir-6847-3p
;
hsa-mir-205-5p
;
hsa-mir-506-5p
;
hsa-mir-892c-5p
;
hsa-mir-31-3p
;
hsa-mir-136-5p
;
hsa-mir-4716-5p
;
hsa-mir-6868-3p
;
hsa-mir-335-3p
;
hsa-mir-5096
;
hsa-mir-513b-5p
;
hsa-mir-6804-5p
;
hsa-mir-125b-2-3p
;
hsa-mir-4457
;
hsa-mir-4446-5p
;
hsa-mir-578
;
hsa-mir-3679-3p
;
hsa-mir-6832-3p
;
hsa-mir-329-5p
;
hsa-mir-6748-5p
;
hsa-mir-6880-5p
;
hsa-mir-4483
;
hsa-mir-1293
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-5192
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/3941657; hsa-let-7i/Downstream/922296;
Nearest TSS
ENST00000382841/Upstream/25621;
ENST00000550319/Downstream/2185;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/273412
,
chr12-CpG: 180/Downstream/1755
Upstream sequence
AAGTGGCATCAGGGATAGGCCATCACAAGTACACAGGATTTCAGTAGGCATTCTGGACTGGAATCCAATCCACACAGATATTGAAGCAGAAAAGTGATAG
Downstream sequence
TCAAGAGAAAAAATTGGAAAGAGATGAGAAGGCAGATTGTGAAGGGTCCTAAGTGTATGGCTAAGGAATTTAGACTGTATTTGTGTGCAATGGAAACCCT
Target sequence
GGAGGGAATAGGGTGAACTGTGAGAAAGAAAATA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT2
Sample type
PBMC
Age
25
Gender
Female
CpG Island Information
×
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