Basic Information
VIS ID
TVIS30014923
Fusion event
HIV-chr12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
47747147/47353364 (Hg38)
End
47747355/47353364 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12A
Nearest miRNA
hsa-mir-1244-3/Upstream/165473; hsa-let-7i/Downstream/10822;
Nearest TSS
ENST00000382841/Upstream/74343; ENST00000550019/Downstream/390;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/117467, chr12-CpG: 69/Downstream/352170
Nearby gene
LINC02416(+355) ;
Upstream sequence
tgtaaatgctatgtaaatagttgttgcattgtgttggttttttatttgtttttttgttgttgttgtcattttaatttttttcagacatttttggtctatg
Downstream sequence
ccctgcctctataaaaaatacaaaaattaggtgggcatggtagtctgtgaatgtagttccagctacttgggaggttgaggtggaaggatcacttgacccc
Target sequence
gttggttgtatttgcagatgcagaatcctcatatacagagggccagctgTAACTCATATGTTTTCAAGAGGATCTTCTCAATATAACAATGTGTAGCTTATggccaggcacagtggcacacgcctgtaatcccagcactttgagatgccaaggctggcagatctcttgagctcaggagtttgagaccagcctgcaaaacacagtgaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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