Basic Information
VIS ID
TVIS30014930
Fusion event
HIV-LIMA1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.12
Reference genome
End
50581379/50187467 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/1415430; hsa-let-7i/Downstream/46675;
Nearest cancer related gene
LIMA1(TSG, No orient, 0)
Upstream sequence
AAATGCCTTTCATTCCTTCCAATTTGTGTAAAATATCTAGGTAATGAAACTGAAATTCTTCACCACACAGCAAATGGTTGGGCCAGCCCTGTGCAGCCTT
Downstream sequence
AAAAGATTCTAGACACTCTTCTAGCATAATTTTGACAGCTTTGCAAGCCAGCATAAAACCTCCCACTGTGTCTTCAGGGGGAGGAACAGCTGGCAGGGTA
Target sequence
AACCCTTCCTCTAATTTTCTGTGAAACTCTATGAAAGCATTTTGGGGAATATTCATATCTTAAATAGAGTGCTCTACACAGAGAAGAAAGGACAGTCCTCTGAAAAGGCAGTAATAGTGAGTGAGTGAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate