Basic Information
VIS ID
TVIS30014932
Fusion event
HIV-DIP2B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
51031673/50637890 (Hg38)
End
51031709/50637890 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
DIP2B
Nearest miRNA
hsa-mir-1244-3/Upstream/403678; hsa-let-7i/Downstream/2260999;
Nearest TSS
ENST00000382841/Upstream/132783; ENST00000546719/Downstream/2915;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/132509, chr12-CpG: 139/Downstream/125825
Upstream sequence
CAGAATTAAAAGATAACATGTGGAGGCTGGTGGCTTCCTTCCATCTTCCTGAGTGGAAATGTGTAGTTTTTTGCTACTAAATACCATTTTTTTCAGATTA
Downstream sequence
GACTCTGATGTATTTTTCTGCCAAGGAACAATAACTTACATACATATTGATCATTGAGAAGGAAGGCTTTATGTTTTTGAACCTAAAATGTGTACTTTTT
Target sequence
TCATCCTTACCATATTCAAACAATAGAAACATATTA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate