Basic Information
VIS ID
TVIS30014945
Fusion event
HIV-TESPA1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
55365350/54971566 (Hg38)
End
55365300/54971566 (Hg38)
Orient
-
Location type
Intronic
Target gene
TESPA1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-589-3p ; hsa-mir-8063 ; hsa-mir-96-3p ; hsa-mir-2681-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-551b-5p ; hsa-mir-185-3p ; hsa-mir-3151-5p ; hsa-mir-3159 ; hsa-mir-4283 ; hsa-mir-4489 ; hsa-mir-4651 ; hsa-mir-4675 ; hsa-mir-4687-3p ; hsa-mir-4741 ; hsa-mir-608 ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6782-5p ; hsa-mir-92a-2-5p ; hsa-mir-1910-3p ; hsa-mir-2682-5p ; hsa-mir-342-3p ; hsa-mir-34b-5p ; hsa-mir-4423-3p ; hsa-mir-449c-5p ; hsa-mir-5692a ; hsa-mir-6511a-5p ; hsa-mir-6808-5p ; hsa-mir-6818-3p ; hsa-mir-6893-5p ; hsa-mir-940
Nearest miRNA
hsa-mir-1244-3/Upstream/634252; hsa-let-7i/Downstream/2222938;
Nearest TSS
ENST00000382841/Upstream/8869; ENST00000547559/Downstream/1988;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/382759, chr12-CpG: 33/Downstream/674638
Upstream sequence
ACACACTTAAACAGAATTAGAAAACAGAGGAAATTGGAAAATGTTCTGACTCCAACAATTCCCCTTCCAAAGACAAATGCAAGTCTGTTGATTAACTCTT
Downstream sequence
TATGGCCATTTTGAAGTTTAAATATTTGAAATCTTTTCAAAACACAGATACATAATGAAAATGTAACAGATACCCTTGCACCAGTCACTCTATTTTCACA
Target sequence
TCCAACAATTCCCCTTCCAAAGACAAATGCAAGTCTGTTGATTAACTCTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate