Basic Information
VIS ID
TVIS30014946
Fusion event
HIV-PYM1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
56314112/55920328 (Hg38)
End
56314150/55920328 (Hg38)
Orient
+
Location type
Intronic
Target gene
PYM1
miRNAs that regulate target gene
hsa-mir-21-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/1583014; hsa-let-7i/Downstream/1274176;
Nearest TSS
ENST00000382841/Upstream/77362; ENST00000550115/Downstream/6783;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/89800, chr12-CpG: 24/Downstream/6627
Upstream sequence
CTAgttgctcatgcctataatcccaacacttcaggaggccaaggtgagaggatcacttgaacccaggagttggagacctgcctgggaaacatagcaagac
Downstream sequence
ggtggctcatgcctgtaattctagcattctgggaggccaaggtgggcgatcctttgaggccaggagttcaagaccagcctagacaacatggtaaaacacc
Target sequence
ctcatcttacagataatttaaaaaATCAggccgagcac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate