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TVIS30014949
Basic Information
VIS ID
TVIS30014949
Fusion event
HIV-CS integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
56679797/56286013 (Hg38)
End
56680103/56286013 (Hg38)
Orient
+
Location type
Exonic
Target gene
CS
miRNAs that regulate target gene
hsa-mir-122-5p
;
hsa-let-7b-5p
;
hsa-let-7a-3p
;
hsa-mir-193b-3p
;
hsa-mir-324-5p
;
hsa-mir-183-5p
;
hsa-mir-28-5p
;
hsa-let-7a-5p
;
hsa-mir-6515-5p
;
hsa-mir-4443
;
hsa-mir-6846-5p
;
hsa-mir-6848-5p
;
hsa-mir-4697-5p
;
hsa-mir-4488
;
hsa-mir-1237-5p
;
hsa-mir-6894-5p
;
hsa-mir-765
;
hsa-mir-7154-3p
;
hsa-mir-766-5p
;
hsa-mir-4722-5p
;
hsa-mir-4692
;
hsa-mir-4514
;
hsa-mir-4433a-3p
;
hsa-mir-761
;
hsa-mir-3619-5p
;
hsa-mir-214-3p
;
hsa-mir-200b-5p
;
hsa-mir-200a-5p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-4433b-3p
;
hsa-mir-6165
;
hsa-mir-4662b
;
hsa-mir-4426
;
hsa-mir-4647
;
hsa-mir-155-5p
;
hsa-mir-365a-3p
;
hsa-mir-365b-3p
;
hsa-mir-4290
;
hsa-mir-4323
;
hsa-mir-4690-3p
;
hsa-mir-4712-5p
;
hsa-mir-5685
;
hsa-mir-770-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/1948699; hsa-let-7i/Downstream/908491;
Nearest TSS
ENST00000382841/Upstream/5;
ENST00000546789/Downstream/78;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/18666
,
chr12-CpG: 62/Downstream/13883
Upstream sequence
ACCATGTCCACAGTGATTTGGCCCACCACCGTCTTGCCATGTTGCTGCCTGAAAGTCTTAATTCTGGCCTGCTCCTTAGGTATCAGGTCAGCCAATATGT
Downstream sequence
aatggtaaattttatgttatgtatattttacactacttaaaaCATTTAAAAGAATTAGGCAAATGTATTGATATTCCCATCTCACTATACCACTGAGTAA
Target sequence
CTTTCAAATTCTAAAAAGAAAAGTAGAAGGACTAAGCAATGGTCTAAAAGTTTATTAGATTTCCTGCAAAGTAGGTGTGTCAAGAATTTGCTTTTTAGAAGCTGGCTTTATCTGCCAGGGAAGTCTGGTCAACTACTCTGCACAAATGAGGGTAAAAGAATTAGGCAgggggaagaaggaatgaggagttaatgtttaatgggaacagtttctcggtttgggcagacaaaagttctggagatggatggttgcaca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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