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TVIS30014960
Basic Information
VIS ID
TVIS30014960
Fusion event
HIV-R3HDM2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
57761133/57367350 (Hg38)
End
57761420/57367350 (Hg38)
Orient
+
Location type
Intronic
Target gene
R3HDM2
miRNAs that regulate target gene
hsa-mir-671-5p
;
hsa-mir-125b-5p
;
hsa-let-7c-5p
;
hsa-mir-6895-5p
;
hsa-mir-1972
;
hsa-mir-6079
;
hsa-mir-7977
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6828-5p
;
hsa-mir-4755-3p
;
hsa-mir-4786-3p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-5693
;
hsa-mir-6715b-5p
;
hsa-mir-4269
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-5582-5p
;
hsa-mir-1299
;
hsa-mir-3202
;
hsa-mir-4493
;
hsa-mir-4533
;
hsa-mir-6128
;
hsa-mir-875-3p
;
hsa-mir-518c-5p
;
hsa-mir-383-3p
;
hsa-mir-514a-5p
;
hsa-mir-4753-5p
Nearest miRNA
hsa-mir-1228/Upstream/172774; hsa-let-7i/Downstream/145338;
Nearest TSS
ENST00000382841/Upstream/25868;
ENST00000547552/Downstream/63440;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/123460
,
chr12-CpG: 99/Downstream/107942
Nearby gene
R3HDM2
(No orient, 56887)
Upstream sequence
cctcataccagtgaactaaagctaaagcatccatgacaggaaagttcaatagaactttctgtgatgatgaaactggggctactaagtatttgaattgtag
Downstream sequence
gtgctcaaacttctttcttttctctcaggaatcactgttctatgctactctttgtccaatatctgaaaacattttttcatatactttgtccaattattca
Target sequence
ttagtgtaactgaggaactcaatttttatgtaaatatccacatgtagctagtggctactgtattacacagtgtaggtttaggggaaccctctgcaaatttccagagctctctttttcttaagaagctctctcctcttaaatattctgccacacaattccagctgccttggcttctcgattcctacctctgtctcctcaattcaagattgccagctctgtatgtgtatccctcccaaccctagtttcaacccagaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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