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TVIS30014964
Basic Information
VIS ID
TVIS30014964
Fusion event
HIV-USP15 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
62749267/62355486 (Hg38)
End
62749102/62355486 (Hg38)
Orient
-
Location type
Intronic
Target gene
USP15
miRNAs that regulate target gene
hsa-mir-103a-3p
;
hsa-mir-16-5p
;
hsa-let-7b-5p
;
hsa-mir-149-5p
;
hsa-mir-222-3p
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-545-3p
;
hsa-mir-6838-5p
;
hsa-mir-33a-3p
;
hsa-mir-105-5p
;
hsa-mir-607
;
hsa-mir-548e-5p
;
hsa-mir-3148
;
hsa-mir-4668-5p
;
hsa-mir-5584-5p
;
hsa-mir-7853-5p
;
hsa-mir-3671
;
hsa-mir-548c-3p
;
hsa-mir-5089-5p
;
hsa-mir-627-5p
;
hsa-mir-4713-5p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-5589-5p
;
hsa-mir-4731-5p
;
hsa-mir-924
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-150-5p
;
hsa-mir-6078
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-512-3p
;
hsa-mir-4438
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-4668-3p
;
hsa-mir-541-5p
Nearest miRNA
hsa-mir-1228/Upstream/95032; hsa-let-7i/Downstream/248200;
Nearest TSS
ENST00000382841/Upstream/58;
ENST00000552346/Downstream/36876;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/94590
,
chr12-CpG: 50/Downstream/111117
Upstream sequence
ATTCGGAACCTGGAAGAAACAATGAACAGCCAGGCCTCTGTGGCCTAAGTAACTTGGGAAATACGTGTTTCATGAACTCAGCTATTCAGGTAGGTCTTTG
Downstream sequence
TAAACAAAATGAAACTCATGTTTCATGGAAATCTGTAATACAAGAAGATAAAGTTGGGTTTTTCATGCCAGAACATGAGTATATGTTTTGAAAGTTCATT
Target sequence
TTCTTCCAGTGTGAAAAACTCAAATTACTGTCTTCCATCATATACCGCTTATAAGAACTATGATTATTCGGAACCTGGAAGAAACAATGAACAGCCAGGCCTCTGTGGCCTAAGTAACTTGGGAAATACGTGTTTCATGAACTCAGCTATTCAGGTAGGTCTTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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