Basic Information
VIS ID
TVIS30014965
Fusion event
HIV-MON2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
62959923/62566143 (Hg38)
End
62960038/62566143 (Hg38)
Orient
+
Location type
Intronic
Target gene
MON2
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-21-5p ; hsa-mir-4684-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-6771-3p ; hsa-mir-105-5p ; hsa-mir-1262 ; hsa-mir-20a-3p ; hsa-mir-217 ; hsa-mir-340-3p ; hsa-mir-3646 ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4701-3p ; hsa-mir-616-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6807-3p ; hsa-mir-6827-3p ; hsa-mir-6849-3p ; hsa-mir-7853-5p ; hsa-mir-3675-3p ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-1228/Upstream/305689; hsa-let-7i/Downstream/37543;
Nearest TSS
ENST00000382841/Upstream/191; ENST00000546751/Downstream/12311;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/99068, chr12-CpG: 165/Downstream/36236
Upstream sequence
TCCTAAAATTGTCCTAACCTCTTGGCAACAAATAAAGTACATCTTTCCCGGTTCTTGGTAGAATGCTGTATGTGCTTTTTCCAATAGTTTTAATTTTTGC
Downstream sequence
AAACAATATGATTAATTTAATCTCAGTTTATTTTTAACTGCATGTGAAAATATTACTTTCTAGGCGGAATGGGTAGCCTTGAATTATGTGCCGTTTGCTG
Target sequence
CTGGCTGAAAATTATTTTTTTCATGAAGTACATATCTCTTTGAAAACTTTGCATGTAATATAATCTGACCTAAAACCAAGGCCTGAACTTTAAGACAAAGATGCTTTCTCTTTGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate