Basic Information
VIS ID
TVIS30014973
Fusion event
HIV-LOC105369844 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
76216573/75822793 (Hg38)
End
76216493/75822793 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105369844
Nearest miRNA
hsa-let-7i/Upstream/6237970; hsa-mir-1178/Downstream/3596464;
Nearest TSS
ENST00000382841/Upstream/123977; ENST00000549888/Downstream/141647;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/311055, chr12-CpG: 142/Downstream/208270
Nearby gene
PHLDA1(No orient, 202653)
Upstream sequence
GCAGACTGAGGAAGGAGCAAGGGTGGAGCAGACACGAAGATGAGAGCAAGGCTGTCTCTAGGCTTTCTCTGATAAATCTGCAGCAGCAAGAGCCTATAAG
Downstream sequence
TGTCAGGGCTAGTTCACGACCACAATCCAGATGGGCTCTGAAACAGGTTTGAGCTGGGGTGGTTAGTAAAGGGCAGTAAATTCAGCTGGAAATACAAAGA
Target sequence
GGGTGGAGCAGACACGAAGATGAGAGCAAGGCTGTCTCTAGGCTTTCTCTGATAAATCTGCAGCAGCAAGAGCCTATAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate