Basic Information
VIS ID
TVIS30014976
Fusion event
HIV-LINC01619 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
92526400/92132624 (Hg38)
End
92526480/92132624 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LINC01619
Nearest miRNA
hsa-let-7i/Upstream/5387475; hsa-mir-1178/Downstream/2429165;
Nearest TSS
ENST00000382841/Upstream/231166; ENST00000618125/Downstream/12609;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1178305, chr12-CpG: 128/Downstream/12310
Nearby gene
BTG1(No orient, 7653)
Upstream sequence
ATATTCATTTTTATGTCTTAACACCAGGGACTTTCTGTAATGCAGGAATAGGCCAGATACTTGCCAGCACCTTAAAAAAAGTTAAGTGTTCCATGCTGTT
Downstream sequence
TAACAAGTCTTTGTACTGTAATCTCAGATTTGGTAAGGAATAGGTGTTTGAGATAACTGAATTTCCCAGGTATTTATATATCAACAAGAAAACTTTTTGT
Target sequence
TAAGTGACTGAATGATAAAGTTAATGTACCCTTGCTTTTCTCTTCAGTCATATATACAAAAGACCAGGGGCTCTAAATGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate