Basic Information
VIS ID
TVIS30014977
Fusion event
HIV-LINC02397 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37/hg19
Start
92870162/92476386 (Hg38)
End
92869992/92476386 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LINC02397
Nearest miRNA
hsa-let-7i/Upstream/5731237; hsa-mir-1178/Downstream/2085403;
Nearest TSS
ENST00000382841/Upstream/9935; ENST00000397833/Downstream/226457;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/329829, chr12-CpG: 133/Downstream/452180
Nearby gene
CLLU1(No orient, 45432)
Upstream sequence
GTTATTATCTGTTTTCAAATTAAAGAAAGTGAGGCATGGTGAGGCTATGTGAtgctataaactgaatgtttttatccccacaaaatttatatgttggaac
Downstream sequence
ctaatcacgaaagtaatcgtgaggccccgtaaaggtagggtctttgggggttgattaggtcatgaaaactccaccttcatgaatgctgttataataataa
Target sequence
caaggtgcctgtcacagaaagaatgtacaataagtgatagctGTGATTTAAATGCCAGTTTTATGTGGAGGTTATTATCTGTTTTCAAATTAAAGAAAGTGAGGCATGGTGAGGCTATGTGAtgctataaactgaatgtttttatccccacaaaatttatatgttggaac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate