Basic Information
VIS ID
TVIS30014980
Fusion event
HIV-ANKS1B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
99745275/99351497 (Hg38)
End
99745617/99351497 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKS1B
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-let-7i/Upstream/1356049; hsa-mir-1178/Downstream/838387;
Nearest TSS
ENST00000382841/Upstream/6526; ENST00000324341/Downstream/34800;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/455901, chr12-CpG: 85/Downstream/632968
Nearby gene
ANKS1B(No orient, 196407)
Upstream sequence
CCTGGAGTTTATTTGCACTATTTTTAGTTTTTAACTTTTTTTTTTTATTTTTGAGAGTTATGGGAATGTTAGTGTTTCAACCTgtgatggtagaaaacac
Downstream sequence
aattccagagattagtactgaggtttcctgCTTAAGCAACAATCTCTTCCTTCCCTTGGGCTCTCTTCACTATGGATGAAGTCTACTATTTAAAGGAAAG
Target sequence
attttaaaataagacagacctgggtttgaattacaaagaacttctaagtcatgtaagcatagataaattagtgtcttttcttaccttcggttttcttctctataaaatgataatgtccagttttccttgttgtcatgaggattagaaataatacagataaaagagcaatcacggtatatgacaaagaacaggtgctcaaattggtggctttatATTTATAGTTAAAGCATAGAAGTATTAAAGTCCTCATGCCtc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate