Basic Information
VIS ID
TVIS30014985
Fusion event
HIV-IFT81 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
GRCh37/hg19
Start
110585436/110147631 (Hg38)
End
110585461/110147631 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
IFT81
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7i/Upstream/314195; hsa-mir-1178/Downstream/1156511;
Nearest TSS
ENST00000382841/Upstream/10824; ENST00000551055/Downstream/24264;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/22736, chr12-CpG: 183/Downstream/132956
Upstream sequence
TAAAAGATTCAAATGAAGGCCATGGCTTATCTGAAAAGAACCAAGGCAGGAGGATTTTAGTGTGAAGAGCACTCTACAACCTCAGAAAATACTAAGCTAC
Downstream sequence
TAGAATtttttaaaacctttataacggaaaatttcaatcaattacaaaggtagaggcaaattgttcaataaaccctcatgtgtccctgagctacagggct
Target sequence
ATAACAAAGCATTATTTAAGGACAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate