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Viral Integration Site DataBase
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TVIS30014993
Basic Information
VIS ID
TVIS30014993
Fusion event
HIV-BICDL1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.23
Reference genome
GRCh37/hg19
Start
120443204/120005400 (Hg38)
End
120443271/120005400 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
;
FRA12C
Target gene
BICDL1
miRNAs that regulate target gene
hsa-mir-4260
;
hsa-mir-1227-5p
;
hsa-mir-3678-3p
;
hsa-mir-7847-3p
;
hsa-mir-6880-5p
;
hsa-mir-4483
;
hsa-mir-1293
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-6816-5p
;
hsa-mir-3196
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-128-2-5p
;
hsa-mir-128-1-5p
;
hsa-mir-6845-5p
;
hsa-mir-6762-5p
;
hsa-mir-2861
;
hsa-mir-6894-5p
;
hsa-mir-765
;
hsa-mir-7154-3p
;
hsa-mir-766-5p
;
hsa-mir-661
;
hsa-mir-2467-3p
;
hsa-mir-423-5p
;
hsa-mir-6776-5p
;
hsa-mir-3184-5p
;
hsa-mir-3158-5p
;
hsa-mir-6742-3p
;
hsa-mir-4779
;
hsa-mir-1249-5p
;
hsa-mir-1273a
;
hsa-mir-1273h-5p
;
hsa-mir-149-3p
;
hsa-mir-2278
;
hsa-mir-30b-3p
;
hsa-mir-3192-5p
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-4419a
;
hsa-mir-4510
;
hsa-mir-4519
;
hsa-mir-4716-3p
;
hsa-mir-4728-5p
;
hsa-mir-5693
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-6731-5p
;
hsa-mir-6760-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6794-5p
;
hsa-mir-6797-5p
;
hsa-mir-6798-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
;
hsa-mir-8085
Nearest miRNA
hsa-let-7i/Upstream/291676; hsa-mir-3612/Downstream/150034;
Nearest TSS
ENST00000382841/Upstream/5547;
ENST00000546790/Downstream/59237;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/15138
,
chr12-CpG: 36/Downstream/81482
Upstream sequence
tgtatttcttcatatgtgatacacacatgcacacatgttgtacataacttttctacttattttgctttgtttttgtttgtttttgagagagtcttgctct
Downstream sequence
ggtttaaatgattcttgtgtctcagcctcccaagtagctggaattacaggcgagtgccaccatgcctacccaatttctgtatttttagtagagatgcggt
Target sequence
gtctcccagagtgcggtggctggagtgtagtggcacaatctcggcacactgcaacctccacctcctg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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