Basic Information
VIS ID
TVIS30014994
Fusion event
HIV-chr12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
121142955/120705152 (Hg38)
End
121142869/120705152 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA12E
Nearest miRNA
hsa-let-7i/Upstream/549653; hsa-mir-3612/Downstream/18041;
Nearest TSS
ENST00000382841/Upstream/1285; ENST00000621276/Downstream/3960;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/17476, chr12-CpG: 72/Downstream/5284
Nearby gene
MLEC(No orient, 3288)
Upstream sequence
tttgccagtacaaactgctgcagtgaacatgcttatgcatatatctttgtgcgtatgtgcaggtgtttctttagggaattcctttaaggaattactggat
Downstream sequence
caaacaatatatgcatttaaaaatttgaaagtactgtcctccatgaggctatatgaatttttactcACCAATCTTGTGCTGTGACTttggaatatgccag
Target sequence
ctgctgcagtgaacatgcttatgcatatatctttgtgcgtatgtgcaggtgtttctttagggaattcctttaaggaattactggat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate