Basic Information
VIS ID
TVIS30014995
Fusion event
HIV-SPPL3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
End
121228116/120790683 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7i/Upstream/67417; hsa-mir-3612/Downstream/653590;
Upstream sequence
TCACTAAGTCAAACCCACCTTCTCTTGTAAAGAAACCTTATCTGACCCATTGCTGCTCACCTGACTTGCGGGTCTCTTTATGCTCTTTCTACATGGATAT
Downstream sequence
CAAAATGATTTCATCTGTAGAGCTTCCTCTGATAATAGCTCTATGTTCAGAGGGATTCTGAGGCTATGGTGAGGGTCACCGAAAAAAGGTACTTGCCCCA
Target sequence
CTGGGTCTGTGCCCGGTGAAAACTGGGCAAATACAACTAGGTTGACAGCGTGCTATAATAACTGGAGAAACTAAGATACACAATAAGTGATCTCTTTTCAATTTAACATCCATGGTCCTCCAATCAATATTTGATCTACCTTTTAATTAGATCTCTAGCATTTCCTCTCTCTTAGGTGGCGACCTTACCCTGTTCTATAGGTCGTGATCTCTGTGCCTGTTATTATATGTTCCCCTAACCTGAAATGACGACTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate