Basic Information
VIS ID
TVIS30014997
Fusion event
HIV-chr12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
121673783/121235980 (Hg38)
End
121673873/121235980 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12E
Nearest miRNA
hsa-let-7i/Upstream/512714; hsa-mir-3612/Downstream/208293;
Nearest TSS
ENST00000382841/Upstream/13648; ENST00000557474/Downstream/24562;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/25519, chr12-CpG: 27/Downstream/38063
Nearby gene
CAMKK2(No orient, 1711)
Upstream sequence
tcacattttggaaacttcatccccaaggcaaccttattgggaggtgaagccttggggaggtgactgagtcaggattgcgctgccctcatgaatggggttg
Downstream sequence
gatgcggcaccaaggcaccctcttggaagcagagagcagccctcaccagataccaaacctgccagcaccttgatcttgaacttcctggcctccagaaatg
Target sequence
gtgccctatacgagggctagagagggagctcatcccccgtctgccttgccactgtctgccacgcgaggacaagtgttcctccctccaaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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