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TVIS30014999
Basic Information
VIS ID
TVIS30014999
Fusion event
HIV-ZCCHC8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
122974739/122490192 (Hg38)
End
122974658/122490192 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
ZCCHC8
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-1228-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-5787
;
hsa-mir-4505
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-4486
;
hsa-mir-7112-5p
;
hsa-mir-383-3p
;
hsa-mir-1288-5p
;
hsa-mir-6765-3p
;
hsa-mir-3622b-3p
;
hsa-mir-3622a-3p
;
hsa-mir-378a-5p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-3653-5p
;
hsa-mir-3189-3p
;
hsa-mir-212-5p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-3934-5p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-6878-3p
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-6778-3p
;
hsa-mir-4701-5p
;
hsa-mir-664a-5p
;
hsa-mir-4794
;
hsa-mir-4735-5p
;
hsa-mir-1228-3p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-6131
;
hsa-mir-3663-5p
Nearest miRNA
hsa-let-7i/Upstream/1045840; hsa-mir-3612/Downstream/205715;
Nearest TSS
ENST00000382841/Upstream/6030;
ENST00000619123/Downstream/9133;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/67307
,
chr12-CpG: 42/Downstream/10452
Upstream sequence
CTTTGGGCACACAATTAATTTTCTAAAAACAAGTAGAGGGAAAAAAGGATAGTCCACAAGCCTGTTGGTTTTAGATAAAAGGAATCCATCTTTTATAAAC
Downstream sequence
CCCAGAAACTTAGATTTTTTTCTGGCCTAAAATTAATTTTCTACCCAAAACCACATGTCCAAGTCAGGCAATGTAAAAAGTCTGAGCCACAAGGTAAAAG
Target sequence
TTTCTAAAAACAAGTAGAGGGAAAAAAGGATAGTCCACAAGCCTGTTGGTTTTAGATAAAAGGAATCCATCTTTTATAAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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