Basic Information
VIS ID
TVIS30015019
Fusion event
HIV-ZMYM2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.11
Reference genome
GRCh37/hg19
Start
20595970/20021830 (Hg38)
End
20596016/20021830 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZMYM2
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-19b-3p ; hsa-mir-1229-3p ; hsa-mir-23b-3p ; hsa-let-7b-5p ; hsa-mir-103a-2-5p ; hsa-mir-4772-5p ; hsa-mir-383-5p ; hsa-mir-2681-5p ; hsa-mir-1305 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-431-5p ; hsa-mir-5093 ; hsa-mir-3682-3p ; hsa-mir-153-5p ; hsa-mir-651-3p ; hsa-mir-203a-3p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-5696 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-4729 ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5580-3p ; hsa-mir-4789-3p
Nearest miRNA
hsa-mir-1267/Downstream/411948;
Nearest TSS
ENST00000623511/Upstream/61971; ENST00000468677/Downstream/2564;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/62340, chr13-CpG: 24/Downstream/96555
Nearest cancer related gene
ZMYM2(OG, No orient, 0)
Upstream sequence
tcttgtggttctggggttctttctctggccacaggtgctttcttctcatgaatgcacagatcagttttcagccaaaatatgtctgtagatgtagttttaa
Downstream sequence
taagatcagagcttttttgtgcagctccatcatcatcagtactctgtttcccaaattctagctgccttgaaagacttgtgtttcctcaactcagtgaaac
Target sequence
gatcacagatcagttttcagccaaaatacgtcggtagatgtatttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate