Basic Information
VIS ID
TVIS30015023
Fusion event
HIV-KATNAL1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.3
Reference genome
End
30829294/30255034 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-106b-5p ; hsa-mir-186-5p ; hsa-mir-122-5p ; hsa-mir-218-5p ; hsa-mir-196a-5p ; hsa-mir-192-5p ; hsa-mir-103a-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-16-5p ; hsa-let-7d-5p ; hsa-mir-548h-5p ; hsa-mir-548j-5p ; hsa-let-7e-5p ; hsa-mir-511-3p ; hsa-mir-4766-5p ; hsa-mir-6512-5p ; hsa-mir-4522 ; hsa-mir-20a-5p ; hsa-mir-591 ; hsa-mir-100-3p ; hsa-mir-548e-5p ; hsa-mir-6807-5p ; hsa-mir-4793-3p ; hsa-mir-1273g-3p ; hsa-mir-3942-3p ; hsa-mir-5100 ; hsa-mir-205-3p ; hsa-mir-5579-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548i ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-6818-5p ; hsa-mir-297 ; hsa-mir-6790-5p ; hsa-mir-6867-5p ; hsa-mir-4658 ; hsa-mir-3659 ; hsa-mir-567 ; hsa-mir-759 ; hsa-mir-4501 ; hsa-mir-574-5p ; hsa-mir-3664-5p ; hsa-mir-4432 ; hsa-mir-6888-3p ; hsa-mir-4711-3p ; hsa-mir-223-5p ; hsa-mir-3120-5p ; hsa-mir-648 ; hsa-mir-7161-5p ; hsa-mir-892a ; hsa-mir-548u ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-4266 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4779 ; hsa-mir-4455 ; hsa-mir-568 ; hsa-mir-656-3p ; hsa-mir-19a-3p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-3613-5p
Nearest miRNA
hsa-mir-2276/Upstream/6092530; hsa-mir-1267/Downstream/9409000;
Upstream sequence
CCTAAATAAGTACGTGTGCACAATGAACCCTAAGCAAGGGGAATCTTCTCAAGGAAAAGAAAAAAAATCTTGTTCTACTATAATCTACAGATAAATCAAA
Downstream sequence
TTAAAATATTTTTCAAAAAAGTTTTAAAGCCGTATTTTTTCTTACAAGGGATCCATTTCACTAAATATTTTTATACATGTATGTGTATATAGATATTTAC
Target sequence
GATACTTATTTTTGGCAGTAGTAAATCATATCCCTCATCTTATTCTGTGAACAGATACATCTACCTTCTTGTCTTTCCCCATAACTATTTTCATTTATTGCTCATTTCTATTCAGAATACTTA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate