Basic Information
VIS ID
TVIS30015025
Fusion event
HIV-FRY integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
32705980/32131843 (Hg38)
End
32706019/32131843 (Hg38)
Orient
+
Location type
Intronic
Target gene
FRY
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-489-3p ; hsa-mir-3913-3p ; hsa-mir-3973 ; hsa-mir-425-5p ; hsa-mir-802 ; hsa-mir-4517 ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-511-5p ; hsa-mir-4474-5p ; hsa-mir-6830-3p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-2276/Upstream/7969339; hsa-mir-1267/Downstream/7532191;
Nearest TSS
ENST00000623511/Upstream/70979; ENST00000641614/Downstream/122305;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/100077, chr13-CpG: 23/Downstream/179444
Upstream sequence
GGTTCAAAGCATTATCAGCTTAATAATGGGCATGAAATTCTTTCGAATTAAGATGTATCCAGTGGAGGATTTTGAGGCCTCTCTTCAGTTTATGCAGGTA
Downstream sequence
CACTTCCCTTCCTCAAAATGATGAACCTGGAACATGAAAAGCCAATTACTTGTCAATACGGAGAAACATTCTACTGTCTAAATAATTCATGAAGTCCTTT
Target sequence
ATGTCTTAGGCAGGAGAGCTAAGGTGCTCTCAACTTGAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate