Basic Information
VIS ID
TVIS30015026
Fusion event
HIV-MTRF1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
41813656/41239520 (Hg38)
End
41813433/41239520 (Hg38)
Orient
-
Location type
Intronic
Target gene
MTRF1
miRNAs that regulate target gene
hsa-mir-18a-3p ; hsa-mir-26a-5p
Nearest miRNA
hsa-mir-2276/Upstream/138420; hsa-mir-1267/Downstream/328766;
Nearest TSS
ENST00000623511/Upstream/12951; ENST00000483215/Downstream/21066;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/44894, chr13-CpG: 99/Downstream/71595
Upstream sequence
gctgtatcctttatagttcatttaaataaatgtatacacatatatataggaatcaagcaaatgtgagaaaatgtaaacaactgacctcaggtgaaggtta
Downstream sequence
taaaattttcattgtggtatcctttaaattttctgtatgtttaaaaAAAAAAGGTTAGGGAAAAGAAAAATATAGAGCAGATGGCTGTATTCAACTAAAA
Target sequence
tactagatattagatattatacaattatgtttagttttcataggtaatggtagtgtgcttacatcggagaatgccctaagagatctatgtgaaagatttggaaggtaaggtctcatggtgtctgctgtatcctttatagttcatttaaataaatgtatacacatatatataggaatcaagcaaatgtgagaaaatgtaaacaactgacctcaggtgaaggtta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate