Basic Information
VIS ID
TVIS30015037
Fusion event
HIV-chr13 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
77934462/77360327 (Hg38)
End
77934512/77360327 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA13E
Nearest miRNA
hsa-mir-1297/Upstream/11142003; hsa-mir-1267/Downstream/337685;
Nearest TSS
ENST00000623511/Upstream/33277; ENST00000471491/Downstream/175347;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/30590, chr13-CpG: 95/Downstream/337326
Nearby gene
MYCBP2(No orient, 33285)
Upstream sequence
TCAAACTGTATTAGTAACCACAATGTGAGCCTGCAGTGAACAGAAAATTCCACTCACAGTGGCTTACTTATGTAGAGATTGAGGTGTCTCACACAAAAAG
Downstream sequence
TATTTGTCTACTATTCTTACATTATTTTTATTCCCATGCTCATGTTTGCCTTATTGTCACTTGATGGTGGCTACACTGTAAGCCCTGTAGTCACATACCA
Target sequence
GTATCCACAGTAGGTGAGGAATTGGTGTAACAGCTCAGCATTTTCCTTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate