Basic Information
VIS ID
TVIS30015054
Fusion event
HIV-chr13 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
110639972/109987625 (Hg38)
End
110640180/109987625 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1267/Upstream/2456377; hsa-mir-4502/Downstream/353333;
Nearest TSS
ENST00000623511/Upstream/1060; ENST00000411690/Downstream/43942;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/117706, chr13-CpG: 44/Downstream/150556
Nearby gene
COL4A1(No orient, 161337)
Upstream sequence
CAATATTTGGTATAAAATTTAGTTCCACGTTGAAGGGCATCAGCTTAGTGATTCCATGAGTCAAAAGTTCACTTTTCTGTTTCTCCGGTTTCTGACACTC
Downstream sequence
CCAGCATGGATAGTGCAGGCTAAAGAGGCAGTTTGAAGAAGTGGTACCTGGGGATTTGCTCTGAGCCCCAAAGCCATGTGAGGTGAGAGCCTTTCACAGG
Target sequence
GGTTCTTCTGCAAAGGTGGAGGTCCAGGATATCTTCTGCCTCTCAGCTCTTTACTTGAGAAACACCCAAGGCTGGCCCCTGCCGAGCTCTGCAGGAAGACTTCAAGTGCAGTAGGGCCCCTCTGTGCAGCCAGGGCCCACAGGTGATGCTGCCACACATTTTCGTCTTATTCCTTGATAATGAGAAGTATTTGGAGATGCAGAGAGCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate