Basic Information
VIS ID
TVIS30015055
Fusion event
HIV-chr13 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
114901449/114135974 (Hg38)
End
114901282/114135974 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1267/Upstream/872975; hsa-mir-4502/Downstream/108531;
Nearest TSS
ENST00000623511/Upstream/3363; ENST00000643687/Downstream/18717;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2933, chr13-CpG: 43/Downstream/2335
Nearby gene
RASA3(No orient, 3354)
Upstream sequence
GTCACCCTCACCTCCCGGCAAATGAGCACTCCTCTCCCAGTCATGATGGAGAAAACACGCATCTCCCTGACTCACTCCTTAACCCAGCCGCAAACTTCAC
Downstream sequence
TGGGTTAGCCTCGGTCCATTTCACTCCTACATCTCGAAACTGTGGTCGTCTTTACGATACCACAAGAACCTGGGGGGCGGACAGTCCCAGAGAAAAAGTT
Target sequence
AGGCCCAGACGTCAGCAGGGCTGGAGCAGGGCTTCTCTGGTGCTCCTGCTGGCGGCTGAGGTGCACAGTCACCCTCACCTCCCGGCAAATGAGCACTCCTCTCCCAGTCATGATGGAGAAAACACGCATCTCCCTGACTCACTCCTTAACCCAGCCGCAAACTTCAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate