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TVIS30015056
Basic Information
VIS ID
TVIS30015056
Fusion event
HIV-HNRNPC integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
21718225/21250066 (Hg38)
End
21718456/21250066 (Hg38)
Orient
+
Location type
Intronic
Target gene
HNRNPC
miRNAs that regulate target gene
hsa-mir-744-5p
;
hsa-mir-455-3p
;
hsa-mir-505-5p
;
hsa-mir-615-3p
;
hsa-mir-18a-3p
;
hsa-mir-484
;
hsa-mir-342-3p
;
hsa-mir-186-5p
;
hsa-mir-30c-5p
;
hsa-let-7e-5p
;
hsa-mir-877-3p
;
hsa-mir-485-3p
;
hsa-mir-539-3p
;
hsa-mir-136-3p
;
hsa-mir-183-3p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-4533
;
hsa-mir-6775-5p
;
hsa-mir-5090
;
hsa-mir-4517
;
hsa-mir-202-3p
;
hsa-mir-4698
;
hsa-mir-8063
;
hsa-mir-548p
;
hsa-mir-583
;
hsa-mir-1276
;
hsa-mir-4311
;
hsa-mir-548e-5p
;
hsa-mir-224-5p
;
hsa-mir-3924
;
hsa-mir-4539
;
hsa-mir-4724-5p
;
hsa-mir-4511
;
hsa-mir-3133
;
hsa-mir-365b-5p
;
hsa-mir-8052
;
hsa-mir-365a-5p
;
hsa-mir-3199
;
hsa-mir-6503-3p
;
hsa-mir-606
;
hsa-mir-708-5p
;
hsa-mir-28-5p
;
hsa-mir-3139
;
hsa-mir-4699-5p
;
hsa-mir-4773
;
hsa-mir-7850-5p
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-4531
;
hsa-mir-139-3p
;
hsa-mir-4524a-3p
;
hsa-mir-6738-3p
;
hsa-mir-544a
;
hsa-mir-6828-3p
;
hsa-mir-6071
;
hsa-mir-1298-5p
;
hsa-mir-3157-5p
;
hsa-mir-627-3p
;
hsa-mir-6515-3p
;
hsa-mir-1-5p
;
hsa-mir-5000-5p
;
hsa-mir-6781-3p
;
hsa-mir-2682-3p
;
hsa-mir-6877-3p
;
hsa-mir-6819-3p
;
hsa-mir-6731-5p
;
hsa-mir-6783-5p
;
hsa-mir-6824-5p
;
hsa-mir-8085
;
hsa-mir-1323
;
hsa-mir-2053
;
hsa-mir-4432
;
hsa-mir-495-3p
;
hsa-mir-499a-5p
;
hsa-mir-5095
;
hsa-mir-548o-3p
;
hsa-mir-555
;
hsa-mir-5688
;
hsa-mir-6504-3p
;
hsa-mir-7-1-3p
;
hsa-mir-7151-3p
;
hsa-mir-7-2-3p
;
hsa-mir-8087
Nearest miRNA
hsa-mir-6717/Upstream/226680; hsa-mir-1185-1/Downstream/1706884;
Nearest TSS
ENST00000550708/Upstream/15821;
ENST00000554750/Downstream/12611;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/145705
,
chr14-CpG: 50/Downstream/19181
Upstream sequence
AGAGAATATGCAATATGCAAAAATAATAAAACACAGGAAGGTCTTATTTCTAATATAACTGATAATCTATATGAATGAAAATAACAGCATGGTTAGTATG
Downstream sequence
tcttcagtcagcaatttccttgcaaatggttcagcaaaaaaaTAAAATGAAACATGGCAATCCTGGTGGAAGGTATATTAAGAATTCATTAGACTGTTCT
Target sequence
ACTACCTGTATACTAAATTCATTAaaaaatacaaaaattagctggaggtggtggcgcacacctgtagtccaggctactcgggaggccaaggcaggggaattgctgtaacctgggaggcagaggttgcagtgagccgagatcgcaccactgcactccagcctgggcaacggagcgagactccacttcaaaaaaaaaaaagaaaTCcacatttaaatacttaggggtcttttg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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