Basic Information
VIS ID
TVIS30015057
Fusion event
HIV-SUPT16H integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
21845014/21376855 (Hg38)
End
21845040/21376855 (Hg38)
Orient
+
Location type
Intronic
Target gene
SUPT16H
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-296-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-339-5p ; hsa-mir-361-5p ; hsa-mir-186-5p ; hsa-mir-25-3p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-mir-765 ; hsa-mir-218-5p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-30a-3p ; hsa-mir-6842-3p ; hsa-mir-647 ; hsa-mir-6874-5p ; hsa-mir-3127-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-6894-5p ; hsa-mir-766-5p ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-3135b ; hsa-mir-3934-3p ; hsa-mir-6798-5p ; hsa-mir-3670 ; hsa-mir-6854-5p ; hsa-mir-6892-5p ; hsa-mir-1178-5p ; hsa-mir-542-3p ; hsa-mir-6077 ; hsa-mir-1253 ; hsa-mir-494-3p ; hsa-mir-338-5p ; hsa-mir-6763-3p ; hsa-mir-376a-2-5p ; hsa-mir-2861 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-509-3p ; hsa-mir-6128 ; hsa-mir-133a-3p ; hsa-mir-133b ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-6717/Upstream/353469; hsa-mir-1185-1/Downstream/1580095;
Nearest TSS
ENST00000550708/Upstream/18453; ENST00000565098/Downstream/7091;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/75634, chr14-CpG: 80/Downstream/6484
Upstream sequence
attataaaatcccaaacccttgcatttgtcttttaatattctatgtaaagaaataagaagttataaataaagcacttctgtgtgcagtgaatttatgatg
Downstream sequence
catatttcagtagcaagataactagccatttGAAGACCTGGattagccaggcatggtagtaggcacctgtaatcccagctactcgggaggctgaggcagg
Target sequence
gttggctaagtaaaagcacttgaata
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate