Basic Information
VIS ID
TVIS30015062
Fusion event
HIV-chr14 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
35357518/34888312 (Hg38)
End
35357661/34888312 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/3873570; hsa-mir-1185-1/Downstream/2063997;
Nearest TSS
ENST00000550708/Upstream/12665; ENST00000553544/Downstream/93645;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/12992, chr14-CpG: 63/Downstream/94116
Nearby gene
BAZ1A(No orient, 12665)
Upstream sequence
TCTATAGGGCAGCAATCATCTGATAAATTAATCTTAAAATGTTTTCAGCTGTGACTAATCAAATATTTGCACCATTTGGGATGCTGACTTTCAAGAAGCA
Downstream sequence
AGGCTGTAAGCAAGAATCTTGGGCAATTCCTATGGCAACAAACTTGAGTGTTAGCATGAGAAGTGGGCAGTCAAGTTTTAATTTAGAAAGTGCCAATAAG
Target sequence
ACAAATAATCTAATACTACTTTGCCTTTATTTGTTTCCAAGGAATTGGAATTGTAAATGCACTTAGAGTTATCATATGATGATTATCTCTTAGTCATAAGTCAGGATTTTTCGCTCTATAACAATAGCAATTATACTCATTTA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate