Basic Information
VIS ID
TVIS30015063
Fusion event
HIV-chr14 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
35357523/34888317 (Hg38)
End
35357314/34888317 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/3873575; hsa-mir-1185-1/Downstream/2063992;
Nearest TSS
ENST00000550708/Upstream/12670; ENST00000553544/Downstream/93640;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/12997, chr14-CpG: 63/Downstream/94111
Nearby gene
BAZ1A(No orient, 12670)
Upstream sequence
AGGGCAGCAATCATCTGATAAATTAATCTTAAAATGTTTTCAGCTGTGACTAATCAAATATTTGCACCATTTGGGATGCTGACTTTCAAGAAGCAACAAA
Downstream sequence
TAATCTAATACTACTTTGCCTTTATTTGTTTCCAAGGAATTGGAATTGTAAATGCACTTAGAGTTATCATATGATGATTATCTCTTAGTCATAAGTCAGG
Target sequence
AACTTTACAACTATGTGTAGTCTTGATTAGTAGTTCGAATTCTTGCTGTAACAGTGTTGTGTTGGTATGTTCTATATATTGTGTCAGTCTCCAAAATGTAAGTTTCTATAGGGCAGCAATCATCTGATAAATTAATCTTAAAATGTTTTCAGCTGTGACTAATCAAATATTTGCACCATTTGGGATGCTGACTTTCAAGAAGCAACAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate