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TVIS30015064
Basic Information
VIS ID
TVIS30015064
Fusion event
HIV-PRORP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
35685806/35216600 (Hg38)
End
35685717/35216600 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRORP
miRNAs that regulate target gene
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6873-3p
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-2117
;
hsa-mir-148a-5p
;
hsa-mir-7856-5p
;
hsa-mir-3658
;
hsa-mir-744-3p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-431-5p
;
hsa-mir-193a-5p
;
hsa-mir-31-3p
;
hsa-mir-4524a-3p
;
hsa-mir-4726-3p
;
hsa-mir-4781-3p
;
hsa-mir-1182
;
hsa-mir-4524b-3p
;
hsa-mir-1273e
;
hsa-mir-8065
;
hsa-mir-4656
;
hsa-mir-7160-5p
;
hsa-mir-202-3p
;
hsa-mir-98-5p
;
hsa-mir-4500
;
hsa-mir-4458
;
hsa-let-7i-5p
;
hsa-let-7g-5p
;
hsa-let-7f-5p
;
hsa-let-7e-5p
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-mir-4721
;
hsa-mir-4699-5p
;
hsa-mir-7162-3p
;
hsa-mir-4446-3p
;
hsa-mir-6876-5p
;
hsa-mir-4476
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-203b-3p
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-6499-3p
;
hsa-mir-2467-3p
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-1827
;
hsa-mir-6840-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4257
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-4695-5p
Nearest miRNA
hsa-mir-208a/Upstream/4201858; hsa-mir-1185-1/Downstream/1735709;
Nearest TSS
ENST00000550708/Upstream/93841;
ENST00000628955/Downstream/62033;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/93803
,
chr14-CpG: 31/Downstream/75594
Upstream sequence
gtctcactaggttgtccacactggtatatcacattttatttatccattcatcagttgagttgttcctactttttggctatcatgaataatactactgtat
Downstream sequence
gaacatttttgtgcctgtttttgtgttgacatgtgtttttatttctctttagtatatatgtaggagtagaattgtcagttcatatagtaattcttctatt
Target sequence
ttgtccacactggtatatcacattttatttatccattcatcagttgagttgttcctactttttggctatcatgaataatactactgtat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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