Basic Information
VIS ID
TVIS30015086
Fusion event
HIV-TMED10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
End
75606044/75139468 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-7-5p ; hsa-mir-192-5p ; hsa-mir-17-5p ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-1273e ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4722-5p ; hsa-mir-7854-3p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-493-3p ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-302f ; hsa-mir-4474-3p ; hsa-mir-5572 ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-647 ; hsa-mir-92a-1-5p ; hsa-mir-6747-5p ; hsa-mir-4710 ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-6762-3p ; hsa-mir-604 ; hsa-mir-4764-5p ; hsa-mir-6804-5p ; hsa-mir-5681a ; hsa-mir-140-3p ; hsa-mir-6757-5p ; hsa-mir-449b-3p ; hsa-mir-3064-3p ; hsa-mir-4457 ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-597-3p ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-4330 ; hsa-mir-5571-5p ; hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-1273h-5p ; hsa-mir-1288-5p ; hsa-mir-149-3p ; hsa-mir-1910-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3614-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3913-5p ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4433a-3p ; hsa-mir-4478 ; hsa-mir-450a-1-3p ; hsa-mir-4514 ; hsa-mir-4692 ; hsa-mir-4728-5p ; hsa-mir-4786-5p ; hsa-mir-485-5p ; hsa-mir-6500-3p ; hsa-mir-6511a-5p ; hsa-mir-6513-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6884-5p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-887-5p
Nearest miRNA
hsa-mir-208a/Upstream/659264; hsa-mir-1185-1/Downstream/2126750;
Upstream sequence
AATTCCCAACCCCTTTTCTAGTACAGGTGCTACTTCAGACTCTACACCTCTATTCATAACCAAACAGTCAAATTCCTATCTTCAAAGTTGATTTTATTTC
Downstream sequence
CTCAACAAAATCTCTGCTGAGgccaagcgtggtggctcacacctgttatcccaatacttcgagaggctgaggcaggaggatcacttgagcctgggaggtc
Target sequence
TATTCCACATTGTTTAGTTAATCATTCAATTCCCAACCCCTTTTCTAGTACAGGTGCTACTTCAGACTCTACACCTCTATTCATAACCAAACAGTCAAATTCCTATCTTCAAAGTTGATTTTATTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate