Basic Information
VIS ID
TVIS30015089
Fusion event
HIV-chr14 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.11
Reference genome
GRCh37/hg19
Start
90159332/89692988 (Hg38)
End
90159278/89692988 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/12426698; hsa-mir-1185-1/Downstream/4255238;
Nearest TSS
ENST00000550708/Upstream/50317; ENST00000553569/Downstream/231639;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/73621, chr14-CpG: 71/Downstream/8450
Nearby gene
FOXN3(No orient, 73838)
Upstream sequence
TGTATCTTAGCATATTGGGACTTCTATATTTAACTTCTATTAATGCTTTTCAATGCCAGCATGAAAACATGTACCTTAGACAATCGTCCTCAGTGGTATT
Downstream sequence
TCTTATGGGAAGCTGATTAGACTAAATAAAATAATGTAGCAAACTAAACAGGCAAACCTCTGTGGATAAACACTGAAAAAGAATGTTAGAGTTGATTTCT
Target sequence
TTTTCAATGCCAGCATGAAAACATGTACCTTAGACAATCGTCCTCAGTGGTATT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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