Basic Information
VIS ID
TVIS30015099
Fusion event
HIV-BCL11B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
End
99695729/99229215 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1260a/Upstream/4091229; hsa-mir-1185-1/Downstream/880204;
Nearest cancer related gene
BCL11B(OG, No orient, 0)
Upstream sequence
atgaatggatggatggatggatggatggatggatggatggaCGGACGGATAGACGTGAGCTGTGAGAactcaacatctctgaacatcattttctcatctg
Downstream sequence
CTCATTCGACCTCCCGTGGATGTCGGCAgaggcagcgtggctccacaggaagaggggtggcctttcaggaggcaaccaaggacaaatcccagttctgcca
Target sequence
caaagtgaggagaataaagtattagggttgctgtgagggttaaattcaagaaggcacacatgcccagcacaatgcagcacatagcaggccctccatacacagtCCTCATAAGGATCCTAGTGGCATGTATGAGGACTTGCTGATGGCAGAGCCCCCCAGAGCCAAGGCAGTGGAAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate