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TVIS30015099
Basic Information
VIS ID
TVIS30015099
Fusion event
HIV-BCL11B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
99695552/99229215 (Hg38)
End
99695729/99229215 (Hg38)
Orient
+
Location type
Intronic
Target gene
BCL11B
miRNAs that regulate target gene
hsa-mir-186-5p
;
hsa-mir-128-3p
;
hsa-mir-183-5p
;
hsa-mir-32-5p
;
hsa-mir-26b-5p
;
hsa-mir-16-5p
;
hsa-mir-203a-3p
;
hsa-mir-137
;
hsa-mir-552-5p
;
hsa-mir-218-5p
;
hsa-mir-6508-3p
;
hsa-mir-4640-5p
;
hsa-mir-4726-5p
;
hsa-mir-3926
;
hsa-mir-378g
;
hsa-mir-4486
;
hsa-mir-6860
;
hsa-mir-612
;
hsa-mir-5189-5p
;
hsa-mir-3187-5p
;
hsa-mir-1285-3p
;
hsa-mir-330-5p
;
hsa-mir-326
;
hsa-mir-1224-3p
;
hsa-mir-1273d
;
hsa-mir-4311
;
hsa-mir-944
;
hsa-mir-367-3p
;
hsa-mir-92a-3p
;
hsa-mir-92b-3p
;
hsa-mir-25-3p
;
hsa-mir-363-3p
;
hsa-mir-6738-3p
;
hsa-mir-544a
;
hsa-mir-527
;
hsa-mir-518a-5p
;
hsa-mir-2276-3p
;
hsa-mir-4772-3p
;
hsa-mir-330-3p
;
hsa-mir-8070
;
hsa-mir-8066
;
hsa-mir-3119
;
hsa-mir-4713-5p
;
hsa-mir-642a-5p
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-150-5p
;
hsa-mir-6832-3p
;
hsa-mir-4667-3p
;
hsa-mir-1470
;
hsa-mir-3938
Nearest miRNA
hsa-mir-1260a/Upstream/4091229; hsa-mir-1185-1/Downstream/880204;
Nearest TSS
ENST00000550708/Upstream/70799;
ENST00000429450/Downstream/33733;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/52785
,
chr14-CpG: 133/Downstream/16287
Nearest cancer related gene
BCL11B
(OG, No orient, 0)
Upstream sequence
atgaatggatggatggatggatggatggatggatggatggaCGGACGGATAGACGTGAGCTGTGAGAactcaacatctctgaacatcattttctcatctg
Downstream sequence
CTCATTCGACCTCCCGTGGATGTCGGCAgaggcagcgtggctccacaggaagaggggtggcctttcaggaggcaaccaaggacaaatcccagttctgcca
Target sequence
caaagtgaggagaataaagtattagggttgctgtgagggttaaattcaagaaggcacacatgcccagcacaatgcagcacatagcaggccctccatacacagtCCTCATAAGGATCCTAGTGGCATGTATGAGGACTTGCTGATGGCAGAGCCCCCCAGAGCCAAGGCAGTGGAAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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