Basic Information
VIS ID
TVIS30015103
Fusion event
HIV-FMN1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
33162703/32870502 (Hg38)
End
33162628/32870502 (Hg38)
Orient
-
Location type
Intronic
Target gene
FMN1
miRNAs that regulate target gene
hsa-mir-136-3p ; hsa-mir-493-3p ; hsa-mir-432-5p ; hsa-mir-340-5p ; hsa-mir-219b-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-6504-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-3907 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6515-3p ; hsa-mir-1236-3p ; hsa-mir-6777-3p
Nearest miRNA
hsa-mir-1268a/Upstream/1805361; hsa-mir-10393/Downstream/1511567;
Nearest TSS
ENST00000557528/Upstream/9665; ENST00000634750/Downstream/17752;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/151007, chr15-CpG: 32/Downstream/324220
Upstream sequence
GGAGGCTGCCCAAGATCAAATTCACCTTAATGTACCATGATTGGGAGTGAGTATTCTCCATGAAAAAATTTAAGCAGAGGTGACAGGGCCAAGTGAGGAC
Downstream sequence
ATGCTAGTGCGCTTTAGGACTTTTGGAAAGACTTGCAAAGCTGGGCCACTGACTACAGCCTTTGCACGGAATTGTCTAAAGCACCATTCAAAGGTCCCGC
Target sequence
CTTAATGTACCATGATTGGGAGTGAGTATTCTCCATGAAAAAATTTAAGCAGAGGTGACAGGGCCAAGTGAGGAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate