Basic Information
VIS ID
TVIS30015113
Fusion event
HIV-FSIP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
39975091/39682890 (Hg38)
End
39975270/39682890 (Hg38)
Orient
+
Location type
Intronic
Target gene
FSIP1
miRNAs that regulate target gene
hsa-mir-181a-5p
Nearest miRNA
hsa-mir-1233-1/Upstream/2709989; hsa-mir-10393/Downstream/2008695;
Nearest TSS
ENST00000557528/Upstream/64647; ENST00000564211/Downstream/64557;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/101524, chr15-CpG: 58/Downstream/99554
Upstream sequence
ATGAAATGACAAAAATTGCAAAAACTTTTAATAGCATTTAAATTTTAATACTCTAATCACATGTGTTTATATTTAAATAAATGTTGGTTTCTTAAAATAC
Downstream sequence
CCAGGTGGGTTCTTGGAAAACAGGTCAGCAGAAGTTAACAGGGTGGTCACTAGCCCAGTGAGCCAACTGTTTCCAAAACACTGGTCCAAACACAAGCCTA
Target sequence
GATTATTCCCAAACTCTCTTGCTATAAATTAAAACACAAATGGAAGACGAAGATGCCCAGAGATGATTCCAGTTGATGGAAGTTCCTGGTCCAGTACAGAAAGGGAAAGAGAATAACAATAAATATAAGTCAAAAGAAGGGTGGAAACAAAATACACTGGCAGTAAAGGCATGTTGGTA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate