Basic Information
VIS ID
TVIS30015115
Fusion event
HIV-BUB1B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
40461684/40169483 (Hg38)
End
40461646/40169483 (Hg38)
Orient
-
Location type
Intronic
Target gene
BUB1B
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-22-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/3196582; hsa-mir-10393/Downstream/1522102;
Nearest TSS
ENST00000557528/Upstream/8416; ENST00000559461/Downstream/14231;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/7988, chr15-CpG: 32/Downstream/69560
Upstream sequence
ttacaaatgaggaaactgaaaacagagttttaagtagcttgtccgtgttactcagcttgtgattggtggagctgaatttgaatctaggttgtcttgttcc
Downstream sequence
agagttcttaactgctgtgTAGTATTAATACTACTTTTCTGTATGTTGTCTTGAAATTTGTTTCTCTAATTTCTATATATTTTCTCTCTCTTCTTATGTT
Target sequence
ttggtggagctgaatttgaatctaggttgtcttgttcc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate