Basic Information
VIS ID
TVIS30015117
Fusion event
HIV-NUSAP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
41629593/41337395 (Hg38)
End
41629519/41337395 (Hg38)
Orient
-
Location type
Intronic
Target gene
NUSAP1
miRNAs that regulate target gene
hsa-let-7b-5p
Nearest miRNA
hsa-mir-1233-1/Upstream/4364494; hsa-mir-10393/Downstream/354190;
Nearest TSS
ENST00000557528/Upstream/4482; ENST00000557840/Downstream/5001;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/4253, chr15-CpG: 22/Downstream/64900
Upstream sequence
ggcgtgagaccctaggcttggccccaccaccaaaccttttagccaccctgcatctacatccacatactctgcttctttgcctgtctaagggcaacctttc
Downstream sequence
catttatgctgaagatcctgggccctcttgcttcccctaggactacattcctacaattagagcctctctcctcattaatttctccactctgctagcttat
Target sequence
ccaccaaaccttttagccaccctgcatctacatccacatactctgcttctttgcctgtctaagggcaacctttc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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