Basic Information
VIS ID
TVIS30015125
Fusion event
HIV-PATL2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
44962777/44670579 (Hg38)
End
44962839/44670579 (Hg38)
Orient
+
Location type
Intronic
Target gene
PATL2
Nearest miRNA
hsa-mir-1233-1/Upstream/876820; hsa-mir-10393/Downstream/47265;
Nearest TSS
ENST00000557528/Upstream/2094; ENST00000632133/Downstream/5040;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/6794, chr15-CpG: 72/Downstream/40683
Upstream sequence
ttgtgcccagACAAGCACGGCCTCTTAACACTCTTTCCTACAACAATCATTCCAGAAATGATGCTGGCACCTTAGGCCCTCCTTGCAGTTATTCTAAAGT
Downstream sequence
CCAGATACCACCACCAAGTCTGATGAAAGGTCAGAGAGCAAAGTGGAGAGCCAGTGAGCAAACCTGTTCCAGCGTCTGTAACCTTCCTGCATTCCTCATG
Target sequence
GTCTTAAGCACCCTGGGCCCCACATCACCCATCTTGGAATTCACATACCAAATACTTAAAGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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