Basic Information
VIS ID
TVIS30015141
Fusion event
HIV-SLC24A1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
65946301/65653963 (Hg38)
End
65945990/65653963 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA15A
Target gene
SLC24A1
Nearest miRNA
hsa-mir-10393/Upstream/891448; hsa-mir-11181/Downstream/65283;
Nearest TSS
ENST00000557528/Upstream/1224; ENST00000563580/Downstream/2122;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/42631, chr15-CpG: 104/Downstream/137538
Upstream sequence
AATGGATTACAGCCAGTTCCAGTCAGCAGCAATGGCTTGTTTTGTGCAATTGTTTTGCTTTTTCTCATGCTTCTGTTTGTGATCTCTTCAATTGCGTCAT
Downstream sequence
GTAAATGGAGAATGAACAAGATCCTGGGCTTCACAATGTTCCTCCTTTACTTTGTATTCCTGATAATCAGTGTGATGTTAGAAGATCGAATCATATCCTG
Target sequence
taatttaatttccctgaaacttaatttccttgtctgtgaaatggggctaataatttctgttcacttcatagatattttattggtggaaaaatactttgtaaagtataaactactatttaagtgtatgggattattatAAACATTAAGGATATTCACATCGTTTCTTCAATCTTGCAGCTTGCCTGTTCCTTGGTTGCTTTTCTCTCTTATCAATGGATTACAGCCAGTTCCAGTCAGCAGCAATGGCTTGTTTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate