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TVIS30015146
Basic Information
VIS ID
TVIS30015146
Fusion event
HIV-NPTN integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
73910706/73618365 (Hg38)
End
73910473/73618365 (Hg38)
Orient
-
Location type
Intronic
Target gene
NPTN
miRNAs that regulate target gene
hsa-mir-1-3p
;
hsa-mir-26b-5p
;
hsa-mir-455-3p
;
hsa-mir-125b-5p
;
hsa-let-7b-5p
;
hsa-mir-1183
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-224-5p
;
hsa-mir-190a-3p
;
hsa-mir-5011-5p
;
hsa-mir-6083
;
hsa-mir-218-5p
;
hsa-mir-1277-5p
;
hsa-mir-4291
;
hsa-mir-494-3p
;
hsa-mir-761
;
hsa-mir-3619-5p
;
hsa-mir-214-3p
;
hsa-mir-922
;
hsa-mir-3617-3p
;
hsa-mir-3074-3p
;
hsa-mir-3646
;
hsa-mir-646
;
hsa-mir-3662
;
hsa-mir-548c-3p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-513a-5p
;
hsa-mir-938
;
hsa-mir-4328
;
hsa-mir-205-3p
;
hsa-mir-4282
;
hsa-mir-129-1-3p
;
hsa-mir-129-2-3p
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10393/Upstream/318386; hsa-mir-11181/Downstream/792992;
Nearest TSS
ENST00000557528/Upstream/54873;
ENST00000561416/Downstream/14398;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/175097
,
chr15-CpG: 97/Downstream/14327
Upstream sequence
GAGTTAAAAAAAATATATGTTAGAAAGATCTCTACCATACAAAGAAAGTCATTAAACAGCTATTAGGAAATGCAAAAATACCCACTCACAATATGGAAAC
Downstream sequence
ACTCCTGCTCAATAAACACCAGTCATCTAAACTTTTATATTACACTTAGAATATGGAACCACTACCTCTCTGTCTAAAAAGGATTAAAATAGAATTTAAA
Target sequence
CGCCTGCCTGGAATTCTTTCTGCCTCGATGTCCTCACTTCCATCAGGAATTAATTTCCTTTGTGACTAGGCCTTGAAGACCAGCTGAGCTGTTTCTGAGAAACATGGGCATTATGACCCTTTGGGGATTAAAAGAGTTAAAAAAAATATATGTTAGAAAGATCTCTACCATACAAAGAAAGTCATTAAACAGCTATTAGGAAATGCAAAAATACCCACTCACAATATGGAAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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