Basic Information
VIS ID
TVIS30015146
Fusion event
HIV-NPTN integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.1
Reference genome
End
73910473/73618365 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/318386; hsa-mir-11181/Downstream/792992;
Upstream sequence
GAGTTAAAAAAAATATATGTTAGAAAGATCTCTACCATACAAAGAAAGTCATTAAACAGCTATTAGGAAATGCAAAAATACCCACTCACAATATGGAAAC
Downstream sequence
ACTCCTGCTCAATAAACACCAGTCATCTAAACTTTTATATTACACTTAGAATATGGAACCACTACCTCTCTGTCTAAAAAGGATTAAAATAGAATTTAAA
Target sequence
CGCCTGCCTGGAATTCTTTCTGCCTCGATGTCCTCACTTCCATCAGGAATTAATTTCCTTTGTGACTAGGCCTTGAAGACCAGCTGAGCTGTTTCTGAGAAACATGGGCATTATGACCCTTTGGGGATTAAAAGAGTTAAAAAAAATATATGTTAGAAAGATCTCTACCATACAAAGAAAGTCATTAAACAGCTATTAGGAAATGCAAAAATACCCACTCACAATATGGAAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate